The Human Mane 5

The Human Mane 5 are the human counterparts of Rainbow Dash, Applejack, Pinkie Pie, Fluttershy and Rarity.

Human Rarity's relationship with Emerald
In Emerald the Great Fashion, when Emerald accidentally fell into the mud. Human Rarity got her out and her boots were muddy. At her house, she gave her a quick bath and cleaned her up. Then, Emerald cleaned Human Rarity's boots all sparkly, shiny and cleaned and they became friends ever since.

Trivia

 * The Human Mane 5 will meet Pooh and his friends in Pooh's Adventures of My Little Pony Equestria Girls.
 * The Human Mane 5 will meet Thomas, Ash and their friends in Thomas' Adventures of My Little Pony: Equestria Girls.
 * The Human Mane 5 will meet Emerl and his friends in Team Robot In Thomas and Friends: Sodor's Legend of the Lost Treasure whenever Twilight and her friends aren't available.
 * The Human Mane 5 will make their guest starring appearance in Pooh's Adventures of Mumfie's Quest: The Movie, Pooh's Adventures of Thomas & Friends: Tale of the Brave, Winnie the Pooh and The Magic Roundabout, Pooh's Adventures of Titan A.E., Pooh's Adventures of Kiki's Delivery Service and Winnie the Pooh and The Trumpet of the Swan whenever Twilight and her friends aren't available.
 * The Human Mane 5 will make their guest starring appearance in Thomas the Tank Engine Meets the Hunchback of Notre Dame, Thomas' Adventures of We're Back: A Dinosaur's Story and Thomas and Twilight Sparkle's Adventures Chronicles whenever Twilight and her friends aren't available.
 * The Human Mane 5 will meet Tino and his friends in Weekenders Adventures of My Little Pony: Equestria Girls.