Ratigan

Professor Ratigan is the main villain of Winnie the Pooh in The Adventures of the Great Mouse Detective, voiced by the late Vincent Price. Ratigan arranges for the kidnapping of both Christopher Robin and Mr. Flaversham, father of Olivia, to (unwillingly) aid him in his plot to take over the throne of mouse London, and later has Olivia and Pooh abducted as leverage. However, he reckoned without the ingenuity of his arch enemy, Detective Basil of Baker Street, and his new assistant, Dr. Dawson, who, accompanined by Tigger, Piglet, Rabbit, and Eeyore, defeated Ratigan and earned themselves a new enemy.

Trivia

 * Ratigan returned in Winnie the Pooh Meets Snow White and the Seven Dwarfs where he and Figet worked for the Evil Queen.
 * Ratigan will get his revenge on Pooh and the gang in Winnie the Pooh Meets The Incredibles, Winnie the Pooh Meets The Outsiders, Pooh's Adventures of The Princess and the Goblin, Pooh's Adventures of Santa Claus is Comin' to Town, Pooh's Adventures of Rugrats Go Wild, and Winnie the Pooh in Fantasmic! (Tokyo Disney Sea).
 * Ratigan became Timon and Pumbaa's enemy in Timon and Pumbaa's Adventures of The Great Mouse Detective.
 * Ratigan became Danny's enemy in Danny Meets the Great Mouse Detective.
 * Ratigan will be Ash's rival in Ash's Adventures of The Great Mouse Detective.
 * Ratigan made his first guest appearence in a Lion King crossover film in Simba, Timon, and Pumbaa's Adventures of DuckTales the Movie: Treasure of the Lost Lamp where he and Arthur and Cecil worked for Merlock.
 * Ratigan will get his revenge on Ash Ketchum and his friends and become Littlefoot's enemy in Littlefoot and The Adventures of the Great Mouse Detective.
 * In Dave Felis' Adventures, He survived his death thanks to the 1987 Shredder going back in time and had him serve his cause. Unfortunately, Ratigan didn't like him or Krang. Until he serves the 2003-2010 Shredder who is more serious. Unfortunately, he was destroyed along with the Shredder. But that wasn't the end of him, he was resurrected by Komplex of the Toad Empire and Ratigan served his loyalty since Komplex wanted to conquer the Earth and hated incompetents.