Margo is the deutergonist in Despicable Me.
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- She is voiced by Miranda Cosgrove, who also starred in the Nickelodeon shows Drake and Josh and iCarly. Both her characters had older brothers
- Margo Gru will get to see Tino,Sci Twi,Littlefoot,Doraemon and their Friends in Tino's Adventures of Despicable Me
- Margo Gru will get to see Danny,Oopsy and Melody in Danny,Oopsy and Melody's Adventures of Despicable Me